Buyukmandira town is located about 1 km south of the Ergene River, on a flat area. Additionally, there is a stream called Camasir Lake to the west of the town. To the east of the town, there is a dry stream with a bridge. It is surrounded by good pastures with wide plains. To the east is the village of Sinanli, to the north is the village of Katranca, and to the south is the village of Lahana. Winters are very cold, dry, and generally snowy, while summers are very hot.

The name Mandira was given due to the town's involvement in dairy, cheese, and livestock activities. Initially named Mandira when it was established in 1877, the town grew with immigrants arriving in 1926, 1935, and 1951, and it was renamed Buyukmandira. A municipality was established in the town in 1955.