Muratli is a district of Tekirdag province, 23 km from the city center. To the east are the districts of Corlu and Ergene, to the south is Tekirdag, and to the north is the Luleburgaz district of Kirklareli province.

There are no high mountains or valleys in the district. The district's lands generally consist of broad-based and fertile flat areas (plains). While some sections are rugged, their elevations are very low.

Muratli's proximity to Istanbul, its proximity to Tekirdag Port, its proximity to the D-100 Highway, and the fact that the Istanbul-Edirne-Europe railway passes through Muratli have made it a preferred region for industrial establishments.

One of the features that makes Muratli interesting is that a railway passes right through the middle of the district. Muratli is one of three districts in Turkiye with a railway passing right through the middle. The others are Polatli-Ankara and Nusaybin-Mardin.

The fact that Muratli's center has been inhabited since ancient times is understood from the jars and copper fragments found in the foundations of the city ruins at a location called Zindan Ustu (now Sari Bayir), near the Inanli Agricultural Enterprise (formerly known as the Inanli cowshed and stallion storage). The Muratli Baglar area is also known to be an ancient settlement.